The general workflow of NGS (Next-Generation Sequencing) can be divided into four key stages:
Sample Preparation
Library Construction
Quality Control
Sequencing Execution
Biowe offers a comprehensive suite of modular solutions for NGS library preparation workstations, empowering automated platforms to achieve fully automated library preparation processes.
Modular Design, Flexible Integration
Our modular solutions are deeply optimized for NGS automation workstations, offering significant advantages such as compact structure, superior performance, and ease of integration, perfectly suited for customized instrument development and platform upgrades.
Key Modules Covering the Entire Workflow
1️⃣ Sample Preprocessing Modules
Grinding Module: Suitable for cell disruption of various sample types, supports multi-sample processing, delivering high grinding efficiency and improving nucleic acid extraction yields.
Ultrasonic Module: Equipped with a cooling system to enable low-temperature sonication of samples. This can be used for cell disruption to enhance nucleic acid extraction efficiency, or to achieve DNA fragmentation.
Nucleic Acid Extraction Module: Automated magnetic bead-based nucleic acid extraction with auto-installing magnetic rod sleeves. The system supports automated cartridge entry and exit controlled by the host computer, making integration with automated platforms seamless.
2️⃣ Library Amplification Module
Automated PCR Amplification Module: Features rapid heating and cooling, supports 96-sample throughput, high temperature control accuracy, stable amplification curves, and compatibility with various reaction systems.
3️⃣ Library Quantification Module
Fluorescence Quantification Module: Utilizes high-sensitivity fluorescence detection technology, enabling rapid and accurate quantification of library concentrations. Open system compatible with general Qubit quantification reagents. Offers optional throughput (8 or 96 samples) and features a compact footprint that conserves deck space.
Empowering Automated Platforms
With over a decade of expertise in optical detection, fluid handling, temperature control, and related fields, Biowe's modular products not only meet functional requirements but also deliver significant advantages in reliability, maintainability, and development timelines for our partners. They are widely applicable for:
High-throughput NGS library preparation workstations
Automated platforms for medical in vitro diagnostics
Customized automation equipment for research applications
In addition to the above module solutions, we also offer automated centrifugation modules, temperature control modules, shaking modules, and more. If you require development of other automation modules, please feel free to contact us!
